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Nat Prod Res. 2007 Jan;21(1):18-23.

Chemical composition and in vitro antimicrobial activity of the essential oils of flower heads and leaves of Santolina rosmarinifolia L. from Romania.

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  • 1Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimioupoli Zographou, Athens, Greece.


The essential oils of the flower heads and leaves of Santolina rosmarinifolia L. (Compositae) cultivated in Romania were obtained through hydrodistillation and analysed by GC-MS. Forty-two components were identified, representing 92.3-94.0% of the whole composition of the samples. Their in vitro antimicrobial activity against gram-positive and gram-negative bacteria strains and the fungus Candida albicans was determined using the agar-diffusion method and the broth dilution method.

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