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Curr Eye Res. 2007 Jan;32(1):21-5.

Effects of mobile phones on oxidant/antioxidant balance in cornea and lens of rats.

Author information

  • 1Ankara Oncology Hospital. Ankara. Turkey. mehmetbalci2001@yahoo.com

Abstract

PURPOSE:

To investigate the effects of mobile-phone-emitted radiation on the oxidant/antioxidant balance in corneal and lens tissues and to observe any protective effects of vitamin C in this setting.

METHODS:

Forty female albino Wistar rats were assigned to one of four groups containing 10 rats each. One group received a standardized daily dose of mobile phone radiation for 4 weeks. The second group received this same treatment along with a daily oral dose of vitamin C (250 mg/kg). The third group received this dose of vitamin C alone, while the fourth group received standard laboratory care and served as a control. In corneal and lens tissues, malondialdehyde (MDA) levels and activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) were measured with spectrophotometric methods.

RESULTS:

In corneal tissue, MDA level and CAT activity significantly increased in the mobile phone group compared with the mobile phone plus vitamin C group and the control group (p < 0.05), whereas SOD activity was significantly decreased (p < 0.05). In the lens tissues, only the MDA level significantly increased in the mobile phone group relative to mobile phone plus vitamin C group and the control groups (p < 0.05). In lens tissue, significant differences were not found between the groups in terms of SOD, GSH-Px, or CAT (p > 0.05).

CONCLUSIONS:

The results of this study suggest that mobile telephone radiation leads to oxidative stress in corneal and lens tissues and that antioxidants such as vitamin C can help to prevent these effects.

PMID:
17364731
[PubMed - indexed for MEDLINE]
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