Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Chest. 2007 Mar;131(3):856-62.

The role of air nicotine in explaining racial differences in cotinine among tobacco-exposed children.

Author information

  • 1University of Cincinnati, 231 Albert Sabin Way, Room 6603, Cincinnati, OH 45267, USA. Stephen.wilson@uc.edu

Abstract

OBJECTIVE:

African-American children have higher rates of tobacco-associated morbidity. Few studies have objectively measured racial differences in the exposure of children to tobacco smoke. The objective of this study was to test whether African-American children have higher levels of cotinine compared to white children while accounting for ambient measures of tobacco smoke.

SETTING:

Community-based sample of asthmatic children (n = 220) enrolled in an environmental tobacco smoke (ETS) reduction trial.

PARTICIPANTS:

A biracial sample (55% African American) of children with asthma aged 5 to 12 years who were routinely exposed to ETS.

MEASUREMENTS:

We measured cotinine levels in serum and hair samples at baseline, 6 months, and 12 months. We measured the level of ETS exposure over a 6-month period by placing air nicotine dosimeters in the homes of the children at baseline and at 6-month study visits.

RESULTS:

African-American children had significantly higher levels of cotinine at all time points in the study. At the 12-month visit, African-American children had higher levels of serum cotinine (1.39 mug/dL vs 0.80 mug/dL, p = 0.001) and hair cotinine (0.28 ng/mg vs 0.08 ng/mg, p < 0.0001) when compared with white children. In a repeated-measures analysis, African-American children had significantly higher levels of serum cotinine (beta = 0.28, p = 0.04) and hair cotinine (beta = 1.40, p < 0.0001) compared with white children. Air nicotine levels and housing volume were independently associated with higher levels of cotinine.

CONCLUSIONS:

Among children with asthma, African-American children have higher levels of serum and hair cotinine compared with white children.

Comment in

PMID:
17356104
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Write to the Help Desk