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Acta Psychiatr Scand. 2007 Apr;115(4):304-9.

Patterns, predictors and impact of substance use in early psychosis: a longitudinal study.

Author information

  • 1Department of Psychiatry, University of Toronto, Toronto, ON, Canada. jean_addington@camh.net

Abstract

OBJECTIVE:

The purpose was to determine the prevalence of substance use and its impact on outcome 3 years after presentation for a first-episode of psychosis.

METHOD:

Subjects were 203 consecutive admissions to an early psychosis program. Assessments included substance use, positive, negative and depressive symptoms and social functioning. Assessments occurred at baseline, and 1-, 2- and 3-year follow-ups.

RESULTS:

The prevalence of substance misuse was high with 51% having a substance use disorder (SUD), 33% with cannabis SUD and 35% with an alcohol SUD. Numbers with an alcohol SUD declined considerably by 1 year and for cannabis SUD by 2 years. Substance misuse was significantly associated with male gender, young age and age of onset and cannabis misuse with increased positive symptoms.

CONCLUSION:

This study confirms the high rates of substance misuse, in particular cannabis, in first-episode psychosis. It further demonstrates that these rates can be reduced.

PMID:
17355521
[PubMed - indexed for MEDLINE]
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