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Anticancer Res. 2007 Jan-Feb;27(1A):155-64.

Comparative biology of human and canine osteosarcoma.

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  • 1Section of Diagnostic Imaging and Radiation Oncology, Vetsuisse Faculty, University of Z├╝rich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.


Dogs with osteosarcoma provide an important model for the same disease in humans. In this report, the comparative nature of human and canine osteosarcoma including incidence and risk factors, clinical presentation and diagnosis, genetic abnormalities, biologic behaviour and prognostic factors, as well as treatment options are reviewed.

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