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1: BMC Infect Dis. 2007 Mar 8;7:12.Click here to read Click here to read Links

Purulent pericarditis due to co-infection with Streptococcus pneumoniae and Mycobacterium tuberculosis in a patient with features of advanced HIV infection.

Louw A, Tikly M.

Department of Medicine, Chris Hani Baragwanath Hospital, Soweto, South Africa. andrewlouw@hotmail.com <andrewlouw@hotmail.com>

BACKGROUND: Both Mycobacterium tuberculosis and Streptococcus pneumoniae are common pathogens in patients with HIV infection. CASE PRESENTATION: We present an unusual case of purulent pericarditis resulting in cardiac tamponade due to infection with both organisms. We highlight the re-emergence of pneumococcal pericarditis in the HIV era and describe the pitfalls and challenges in the diagnosis of this condition. CONCLUSION: Clinicians working in HIV endemic areas need to consider dual infection with these organisms in patients who respond inadequately to either antibiotics or anti-tuberculous therapy alone.

PMID: 17346343 [PubMed - indexed for MEDLINE]

PMCID: PMC1831473