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Pol Merkur Lekarski. 2006 Nov;21(125):480-3.

[Overlap syndrome autoimmune hepatitis and primary biliary cirrhosis associated with antiphospholipid syndrome].

[Article in Polish]

Author information

  • 1Department of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Poland.


The paper presents diagnostic problems and therapeutic management in a case of 34 year old woman with antiphospholipid syndrome (APS) connected with overlap syndrome: autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). Life threatening cardiac arrhythmia was the first clinical manifestation of the disease. Pulmonary embolism occurred a few months later, with the presence of antiphospholipid antibodies. The diagnosis of AlH and PBC was made as a result of further research of complex immunological disturbances observed in the patient and after liver biopsy.

[PubMed - indexed for MEDLINE]
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