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Clin Infect Dis. 2007 Apr 1;44(7):964-7. Epub 2007 Feb 14.

Neuraminidase inhibitors improve outcome of patients with leukemia and influenza: an observational study.

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  • 1Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77230-1402, USA.


We reviewed the records of 33 patients with leukemia who experienced influenza during the period from October 2000 to March 2004. Three (38%) of the 8 patients who did not receive neuraminidase inhibitor therapy and none of the 25 patients who received it died of influenza pneumonia (P=.001). The use of neuraminidase inhibitor therapy seems to improve the outcome of influenza in patients with leukemia.

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