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Gynecol Obstet Fertil. 2007 Apr;35(4):290-6. Epub 2007 Mar 6.

[Interest in agents for adhesion prevention after gynecologic surgery].

[Article in French]

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  • 1Clinique de gynécologie, hôpital Jeanne-de-Flandre, centre hospitalier régional universitaire (CHRU) de Lille, 2, avenue Oscar-Lambret, 59037 Lille cedex, France.


Adhesion barriers are intraperitoneal agents, solid or fluid, developed in order to prevent postoperative adhesions. In this article, we evaluate the efficiency of these new barrier agents for adhesion prevention in gynaecologic surgery, undertaking a review of controlled clinical trials published. Several human clinical trials demonstrated the safety and efficiency of both Interceed and Seprafilm. As far as other barrier agents are concerned, data are still insufficient to recommend them for clinical use. There is a need for other randomised controlled trials in order to evaluate functional efficiency of anti adhesion agents.

[PubMed - indexed for MEDLINE]
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