Format

Send to:

Choose Destination
See comment in PubMed Commons below
Eur J Med Genet. 2007 May-Jun;50(3):163-75. Epub 2007 Jan 21.

Chromosomal anomalies in the aetiology of oesophageal atresia and tracheo-oesophageal fistula.

Author information

  • 1Department of Paediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands. j.felix@erasmusmc.nl

Abstract

Oesophageal atresia (OA) and tracheo-oesophageal fistula (TOF) are severe congenital anomalies of which the aetiology is largely unknown. Several chromosomal anomalies have been described in patients presenting with these anatomical malformations, but until now none of these has led to the identification of a single aetiological factor. This paper reviews the chromosomal abnormalities reported in cases of OA/TOF and serves as a starting point to identify chromosomal regions harbouring genes involved in the aetiology of OA/TOF.

PMID:
17336605
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk