Send to:

Choose Destination
See comment in PubMed Commons below
Drug Discov Today. 2007 Mar;12(5-6):234-40. Epub 2007 Feb 9.

Computational classification of classically secreted proteins.

Author information

  • 1Stabile 3-15, Department of Laboratory Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.


The ability to identify classically secreted proteins is an important component of targeted therapeutic studies and the discovery of circulating biomarkers. Here, we review some of the most recent programs available for the in silico prediction of secretory proteins, the performance of which is benchmarked with an independent set of annotated human proteins. The description of these programs and the results of this benchmarking provide insights into the most recently developed prediction programs, which will enable investigators to make more informed decisions about which program best addresses their research needs.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk