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Genome Biol. 2007;8(2):204.

Decoding dosage compensation.

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  • 1Department of Pathology, University of Washington, Seattle, WA 98195, USA.

Abstract

How the mechanisms of dosage compensation distinguish the sex chromosomes from the autosomes has been something of a mystery. A recent study in Caenorhabditis elegans has identified clusters of two common DNA motifs as a cis-acting code for the recruitment of the DCC, the protein complex that mediates dosage compensation.

PMID:
17328790
[PubMed - indexed for MEDLINE]
PMCID:
PMC1852422
Free PMC Article

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