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Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Mar;103(3):382-4. Epub 2006 Oct 6.

Nonneural granular cell tumor of the oral cavity: a case report and review of the literature.

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  • 1Section of Oral and Maxillofacial Pathology, New York Hospital Queens, Flushing, NY, USA.


Nonneural granular cell tumors (NNGCTs) are rare benign neoplasms originally described in 1991 by Leboit et al. Typical granular cell tumors (GCTs) are commonly encountered in the oral cavity, but NNGCTs, unlike GCTs, are S-100 negative and may display cytologic atypia, allowing for misdiagnosis as a more aggressive lesion. We report a case of a 43-year-old male with a lesion of the mandible that we believe to be the first intraoral example of an NNGCT.

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