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    Artif Intell Med. 2007 Mar;39(3):237-50. Epub 2007 Feb 22.

    Towards the ontological foundations of symbolic biological theories.

    Source

    Department of Medical Informatics, Freiburg University Hospital, Stefan-Meier-Strasse 26, 79104 Freiburg, Germany. stschulz@uni-freiburg.de

    Abstract

    OBJECTIVE:

    Support for the symbolic representation of the physical structure of living organisms by an ontologically solid and logically sound foundation as a basis for formal reasoning.

    METHODS:

    A set of canonical relations and attributes necessary for empirically adequate descriptions of biological entities is proposed.

    RESULTS:

    It is shown how a broad range of biological organisms and their parts can be represented by cascading theories which are ordered by the dimensions of granularity, development, species, and canonicity.

    CONCLUSION:

    The proposed representation of biological objects is non-redundant and compatible with inter- and intra-species similarities, developmental stages and pathological deviations.

    PMID:
    17321118
    [PubMed - indexed for MEDLINE]

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