Mol Aspects Med. 2007 Oct-Dec;28(5-6):423-36. Epub 2007 Jan 11.

Absorption, transport, and tissue delivery of vitamin E.

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Departamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica, Hospital UC, Marcoleta 367, Santiago, Chile. arigotti@med.puc.cl

Abstract

Vitamin E is one of the most abundant lipid-soluble antioxidant agents found in plasma and cells of higher mammals. The uptake, transport and tissue delivery of alpha-tocopherol, a key vitamin E form, involves molecular, biochemical, and cellular processes closely related to overall lipid and lipoprotein homeostasis. This review highlights recent findings that have led to a better understanding of vitamin E transport, including intestinal absorption, hepatic transport, and cellular uptake of alpha-tocopherol in vivo. This new information may be critical for manipulation of vitamin E homeostasis in a variety of oxidative stress-related disease conditions in humans.

PMID:: 17320165; [PubMed - indexed for MEDLINE]

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TW006153/TW/FIC NIH HHS/United States

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Chemical compound information

Vitamin E

MW: 430.70 g/mol

MF: C₂₉H₅₀O₂

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Absorption, transport, and tissue delivery of vitamin E.
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Mol Aspects Med. 2007 Oct-Dec ;28(5-6):423-36. Epub 2007 Jan 11 .

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