Turner's syndrome (TS) is the most common chromosomal abnormality in female subjects, affecting 1 in 2,500 live female births. The most consistent clinical features associated with this syndrome are short stature and ovarian failure. TS results from the absence of X chromosome or the presence of an abnormal X chromosome. Adults with TS are susceptible to a range of disorders, including osteoporosis, type 2 diabetes mellitus, and coronary artery disease. Coronary artery disease is 1 of the most common causes of morbidity and mortality in patients with TS. In this report, the investigators present an unusual case of a patient with TS diagnosed with multivessel coronary artery disease at a younger age who underwent 3-vessel coronary artery bypass grafting.