Turner's syndrome and coronary artery disease.

Department of Medicine, University of Tennessee Health Science Center, College of Medicine, Memphis, Tennessee, USA.

Turner's syndrome (TS) is the most common chromosomal abnormality in female subjects, affecting 1 in 2,500 live female births. The most consistent clinical features associated with this syndrome are short stature and ovarian failure. TS results from the absence of X chromosome or the presence of an abnormal X chromosome. Adults with TS are susceptible to a range of disorders, including osteoporosis, type 2 diabetes mellitus, and coronary artery disease. Coronary artery disease is 1 of the most common causes of morbidity and mortality in patients with TS. In this report, the investigators present an unusual case of a patient with TS diagnosed with multivessel coronary artery disease at a younger age who underwent 3-vessel coronary artery bypass grafting.

PMID: 17317384 [PubMed - indexed for MEDLINE]