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1: Bioorg Med Chem Lett. 2007 Apr 15;17(8):2123-5. Epub 2007 Feb 2.Click here to read Links

Methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives: a new class of acetylcholinesterase inhibitors.

Wen H, Zhou Y, Lin C, Ge H, Ma L, Wang Z, Peng W, Song H.

School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China.

A new class of inhibitors of acetylcholinesterase (methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives) is described. Compounds 4b and 4i were found to be more potent than galanthamine in inhibiting acetylcholinesterase.

PMID: 17317172 [PubMed - indexed for MEDLINE]