Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Jpn J Infect Dis. 2007 Feb;60(1):23-8.

Effects of oral care on development of oral mucositis and microorganisms in patients with esophageal cancer.

Author information

  • 1Department of Gerodontology, Graduate School, Tokyo Medical and Dental University, Tokyo 113-8549, Japan. syoneda@nih.go.jp

Abstract

We evaluated the effects of special oral care using a toothbrush with combined irrigation and suctioning functions, along with povidone-iodine to treat oral bacteria and mucositis, in esophageal cancer patients undergoing chemoradiotherapy. In the special care group, oral hygiene was performed 3 days a week after dinner. Bacteria in saliva and plague samples were measured at various sampling points after chemoradiotherapy. The incidence of mucositis was significantly reduced in the special care group in comparison with the control group. Total streptococci were significantly decreased in the opportunistic pathogens-positive and lower-level mutans streptococci control group during chemoradiotherapy, but they were not reduced in the opportunistic pathogens-negative and higher-level mutans streptococci control groups or in the special care group. Our results showed that a special oral care regimen enabled the total population of streptococci microflora to remain stable, was negatively correlated with opportunistic pathogens and positively correlated with mutans streptococci infection, and prevented the development of mucositis.

PMID:
17314421
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for National Institute of Infectious Diseases
    Loading ...
    Write to the Help Desk