Science. 2007 Feb 16;315(5814):998-1000.

The Calyptogena magnifica chemoautotrophic symbiont genome.

Newton IL, Woyke T, Auchtung TA, Dilly GF, Dutton RJ, Fisher MC, Fontanez KM, Lau E, Stewart FJ, Richardson PM, Barry KW, Saunders E, Detter JC, Wu D, Eisen JA, Cavanaugh CM.

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Harvard University, 16 Divinity Avenue, Biolabs 4080, Cambridge, MA 02138, USA.

Abstract

Chemoautotrophic endosymbionts are the metabolic cornerstone of hydrothermal vent communities, providing invertebrate hosts with nearly all of their nutrition. The Calyptogena magnifica (Bivalvia: Vesicomyidae) symbiont, Candidatus Ruthia magnifica, is the first intracellular sulfur-oxidizing endosymbiont to have its genome sequenced, revealing a suite of metabolic capabilities. The genome encodes major chemoautotrophic pathways as well as pathways for biosynthesis of vitamins, cofactors, and all 20 amino acids required by the clam.

PMID:: 17303757; [PubMed - indexed for MEDLINE]

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Complete genome sequence of Candidatus Ruthia magnifica. [Stand Genomic Sci. 2010]
Complete genome sequence of Candidatus Ruthia magnifica.
Roeselers G, Newton IL, Woyke T, Auchtung TA, Dilly GF, Dutton RJ, Fisher MC, Fontanez KM, Lau E, Stewart FJ, et al. Stand Genomic Sci. 2010 Oct 27; 3(2):163-73. Epub 2010 Oct 27.
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Cited by 14 PubMed Central articles

Metaproteomics of a gutless marine worm and its symbiotic microbial community reveal unusual pathways for carbon and energy use. [Proc Natl Acad Sci U S A. 2012]
Metaproteomics of a gutless marine worm and its symbiotic microbial community reveal unusual pathways for carbon and energy use.
Kleiner M, Wentrup C, Lott C, Teeling H, Wetzel S, Young J, Chang YJ, Shah M, Verberkmoes NC, Zarzycki J, et al. Proc Natl Acad Sci U S A. 2012 May 8; 109(19):E1173-82. Epub 2012 Apr 18.
On the evolutionary ecology of symbioses between chemosynthetic bacteria and bivalves. [Appl Microbiol Biotechnol. 2012]
On the evolutionary ecology of symbioses between chemosynthetic bacteria and bivalves.
Roeselers G, Newton IL. Appl Microbiol Biotechnol. 2012 Apr; 94(1):1-10. Epub 2012 Feb 22.
Loss of genes for DNA recombination and repair in the reductive genome evolution of thioautotrophic symbionts of Calyptogena clams. [BMC Evol Biol. 2011]
Loss of genes for DNA recombination and repair in the reductive genome evolution of thioautotrophic symbionts of Calyptogena clams.
Kuwahara H, Takaki Y, Shimamura S, Yoshida T, Maeda T, Kunieda T, Maruyama T. BMC Evol Biol. 2011 Oct 3; 11:285. Epub 2011 Oct 3.

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