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J Am Geriatr Soc. 2007 Feb;55(2):234-9.

A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study.

Author information

  • 1Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA. broe@hrca.harvard.edu

Abstract

OBJECTIVES:

To determine the effect of four vitamin D supplement doses on falls risk in elderly nursing home residents.

DESIGN:

Secondary data analysis of a previously conducted randomized clinical trial.

SETTING:

Seven hundred twenty-five-bed long-term care facility.

PARTICIPANTS:

One hundred twenty-four nursing home residents (average age 89).

INTERVENTION:

Participants were randomly assigned to receive one of four vitamin D supplement doses (200 IU, 400 IU, 600 IU, or 800 IU) or placebo daily for 5 months.

MEASUREMENTS:

Number of fallers and number of falls assessed using facility incident tracking database.

RESULTS:

Over the 5-month study period, the proportion of participants with falls was 44% in the placebo group (11/25), 58% (15/26) in the 200 IU group, 60% (15/25) in the 400 IU group, 60% (15/25) in the 600 IU group, and 20% (5/23) in the 800 IU group. Participants in the 800 IU group had a 72% lower adjusted-incidence rate ratio of falls than those taking placebo over the 5 months (rate ratio=0.28; 95% confidence interval=0.11-0.75). No significant differences were observed for the adjusted fall rates compared to placebo in any of the other supplement groups.

CONCLUSION:

Nursing home residents in the highest vitamin D group (800 IU) had a lower number of fallers and a lower incidence rate of falls over 5 months than those taking lower doses. Adequate vitamin D supplementation in elderly nursing home residents could reduce the number of falls experienced by this high falls risk group.

PMID:
17302660
[PubMed - indexed for MEDLINE]
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