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Eur J Gastroenterol Hepatol. 2007 Mar;19(3):277-80.

Infliximab for ulcerative colitis following liver transplantation.

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  • 1Department of Gastroenterology, University Hospitals, Aintree, Liverpool, UK.


Primary sclerosing cholangitis is a chronic cholestatic disease with a progressive course, often culminating in hepatic transplantation. When associated with primary sclerosing cholangitis, ulcerative colitis commonly follows a mild course before, but a more progressive course following liver transplantation, with a significant proportion of patients becoming steroid dependent and/or requiring colectomy. We report the first case demonstrating the efficacy and safety of infliximab therapy for ulcerative colitis following hepatic transplantation.

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