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    J Trauma. 2007 Feb;62(2):287-91; discussion 291.

    Persistent intracranial hypertension treated by hypothermic therapy after severe head injury might induce late-phase cerebral vasospasm.

    Source

    Department of Traumatology and Critical Care Medicine, National Defense Medical College, Saitama, Japan. yangawa@me.ndmc.ac.jp

    Abstract

    BACKGROUND:

    Vasospasm caused by intracranial hypertension in head injury remains controversial.

    METHODS:

    Between 1996 and 2004, we prospectively and consecutively performed conventional cerebral angiography for six patients with head injuries who showed persistent intracranial hypertension (over 20 mm Hg for longer than 5 days) despite performing various treatments for intracranial hypertension.

    RESULTS:

    All subjects had a minor hemorrhage at admission, classified as Fisher group 2. Five of the six patients had angiographically confirmed vasospasm, and one of them later developed a cerebral infarction. Four of the five subjects who exhibited cerebral vasospasm had undergone hypothermic therapy to control the intracranial hypertension.

    CONCLUSION:

    Our results suggest that persistent intracranial hypertension that is treated by hypothermic therapy may be related to late phase cerebral vasospasm.

    PMID:
    17297314
    [PubMed - indexed for MEDLINE]

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