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    Biosci Biotechnol Biochem. 2007 Feb;71(2):571-4. Epub 2007 Feb 7.

    Rhythmic cycle of clathrin-coated pit formation at the trans-golgi network in human MDA-MB-435 cells.

    Source

    Laboratory of Molecular Biology and Cell Informatics, Division of Bioscience and Informatics, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, Japan. ssaka@biochem.osakafu-u.ac.jp

    Abstract

    We studied the in vivo dynamics of enhanced green fluorescent protein-tagged clathrin light chain a (GFP-CLCa) at the trans-Golgi network (TGN) in MDA-MB-435 cells. The intensity of fluorescence signals of GFP-CLCa periodically increased and decreased at the TGN approximately every 100 s. This suggests that the formation of clathrin-coated pits occurs synchronously and periodically at the TGN.

    PMID:
    17284835
    [PubMed - indexed for MEDLINE]
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