Send to

Choose Destination
See comment in PubMed Commons below
Cell Metab. 2007 Feb;5(2):81-3.

A helping hand for cytochrome p450 enzymes.

Author information

  • 1Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.


In this issue of Cell Metabolism, Espenshade and colleagues (Hughes et al., 2007) show that the hemoprotein Dap1/PGRMC1 forms a stable complex with several members of the cytochrome P450 superfamily of enzymes and positively regulates their activities. This action indicates an important role for Dap1/PGRMC1 in P450-catalyzed reactions, some of which are involved in the metabolism of sterols and pharmaceutical compounds.

[PubMed - indexed for MEDLINE]
Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk