University of North Carolina Hospitals, 101 Manning Drive, 1021 East Wing, Blood Bank, CB#7525, Chapel Hill, NC 27514, USA. araba_afenyi-annan@med.unc.edu
This article reviews numerous multi-center clinical trials, either ongoing or in planning stages, which involve diverse clinical applications and emerging technologies in apheresis and transfusion medicine. The investigations summarized herein involve the following specific areas: platelet dosing strategy, thrombotic thrombocytopenia purpura, inflammatory bowel disease, seven-day platelet storage, dendritic cell vaccines, and age-related macular degeneration.