Obstet Gynecol. 1992 Jan;79(1):111-6.

Postmenopausal bleeding from unusual endometrial polyps in women on chronic tamoxifen therapy.

Corley D, Rowe J, Curtis MT, Hogan WM, Noumoff JS, Livolsi VA.

Source

Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia.

Abstract

There are recent reports of postmenopausal bleeding from endometrial polyps in women receiving tamoxifen therapy for breast cancer. We describe four additional patients who presented with vaginal bleeding, and emphasize the pathology. These polyps demonstrated cystically dilated glands in all cases and stromal decidualization in two; in one instance, metastatic breast carcinoma was present in the polyp. The mechanisms by which tamoxifen may affect the development of these polyps are discussed.

PMID:: 1727568; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

Tamoxifen

LinkOut - more resources

Supplemental Content

Related citations

Recurrent endometrial polyps in postmenopausal breast cancer patients on tamoxifen. [Gynecol Oncol. 2003]
Recurrent endometrial polyps in postmenopausal breast cancer patients on tamoxifen.
Biron-Shental T, Tepper R, Fishman A, Shapira J, Cohen I. Gynecol Oncol. 2003 Aug; 90(2):382-6.
Abnormal vaginal bleeding from endometrial polyps in a woman receiving tamoxifen therapy for breast cancer: report of a case. [Surg Today. 1997]
Abnormal vaginal bleeding from endometrial polyps in a woman receiving tamoxifen therapy for breast cancer: report of a case.
Fujikawa T, Nishimura S, Matsusue S, Takeda H. Surg Today. 1997; 27(8):769-72.
[Postmenopausal hemorrhage and endometrial cancer in tamoxifen therapy]. [Zentralbl Gynakol. 1994]
[Postmenopausal hemorrhage and endometrial cancer in tamoxifen therapy].
Krause A, Gerber B. Zentralbl Gynakol. 1994; 116(1):44-7.
Review Metastatic breast lobular carcinoma to tamoxifen-associated endometrial polyp: case report and literature review. [Ann Diagn Pathol. 2005]
Review Metastatic breast lobular carcinoma to tamoxifen-associated endometrial polyp: case report and literature review.
Al-Brahim N, Elavathil LJ. Ann Diagn Pathol. 2005 Jun; 9(3):166-8.
Review Tamoxifen-induced endometrial polyp. A case report and review of the literature. [Eur J Gynaecol Oncol. 1998]
Review Tamoxifen-induced endometrial polyp. A case report and review of the literature.
Nomikos IN, Elemenoglou J, Papatheophanis J. Eur J Gynaecol Oncol. 1998; 19(5):476-8.

See reviews... See all...

Cited by 6 PubMed Central articles

Tumorigenic effects of tamoxifen on the female genital tract. [Clin Med Pathol. 2008]
Tumorigenic effects of tamoxifen on the female genital tract.
Nasu K, Takai N, Nishida M, Narahara H. Clin Med Pathol. 2008; 1:17-34. Epub 2008 Mar 1.
Review The effect of tamoxifen on the genital tract. [Cancer Imaging. 2008]
Review The effect of tamoxifen on the genital tract.
Polin SA, Ascher SM. Cancer Imaging. 2008 Jun 30; 8:135-45. Epub 2008 Jun 30.
Endometrial pathology in postmenopausal tamoxifen treatment: comparison between gynaecologically symptomatic and asymptomatic breast cancer patients. [J Clin Pathol. 1999]
Endometrial pathology in postmenopausal tamoxifen treatment: comparison between gynaecologically symptomatic and asymptomatic breast cancer patients.
Cohen I, Perel E, Flex D, Tepper R, Altaras MM, Cordoba M, Beyth Y. J Clin Pathol. 1999 Apr; 52(4):278-82.

See all...

Chemical compound information

Tamoxifen

MW: 371.51 g/mol

MF: C₂₆H₂₉NO

See 15 citations for this compound....

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Postmenopausal bleeding from unusual endometrial polyps in women on chronic tamo...
Postmenopausal bleeding from unusual endometrial polyps in women on chronic tamoxifen therapy.
Obstet Gynecol. 1992 Jan ;79(1):111-6.

PubMed
Three-dimensional analysis of vacuoles and surface invaginations of capillary en...
Three-dimensional analysis of vacuoles and surface invaginations of capillary endothelia in the eel rete mirabile.
Anat Rec. 1998 Dec ;252(4):546-53.

PubMed
Acute coronary syndromes: unstable angina and non-Q-wave myocardial infarction.
Acute coronary syndromes: unstable angina and non-Q-wave myocardial infarction.
Circulation. 1998 Mar 31 ;97(12):1195-206.

PubMed
Efficacy of bronchodilator therapy in bronchiolitis. A meta-analysis.
Efficacy of bronchodilator therapy in bronchiolitis. A meta-analysis.
Arch Pediatr Adolesc Med. 1996 Nov ;150(11):1166-72.

PubMed
L-acetylcarnitine treatment of mental decline in the elderly.
L-acetylcarnitine treatment of mental decline in the elderly.
Drugs Exp Clin Res. 1994 ;20(4):169-76.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Postmenopausal bleeding from unusual endometrial polyps in women on chronic tamoxifen therapy.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

Supplemental Content

Related citations

Cited by 6 PubMed Central articles

Chemical compound information

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information