Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
Moerke NJ, Aktas H, Chen H, Cantel S, Reibarkh MY, Fahmy A, Gross JD, Degterev A, Yuan J, Chorev M, Halperin JA, Wagner G.
Cell. 2007 Jan 26;128(2):257-67.
Related citations
Different roles for the TOS and RAIP motifs of the translational regulator protein 4E-BP1 in the association with raptor and phosphorylation by mTOR in the regulation of cell size.
Eguchi S, Tokunaga C, Hidayat S, Oshiro N, Yoshino K, Kikkawa U, Yonezawa K.
Genes Cells. 2006 Jul;11(7):757-66.
Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells.
Connolly E, Braunstein S, Formenti S, Schneider RJ.
Mol Cell Biol. 2006 May;26(10):3955-65.
Structural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods.
Tomoo K, Matsushita Y, Fujisaki H, Abiko F, Shen X, Taniguchi T, Miyagawa H, Kitamura K, Miura K, Ishida T.
Biochim Biophys Acta. 2005 Dec 1;1753(2):191-208. Epub 2005 Aug 24.
Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1.
Tee AR, Tee JA, Blenis J.
FEBS Lett. 2004 Apr 23;564(1-2):58-62.
Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors.
Patel J, McLeod LE, Vries RG, Flynn A, Wang X, Proud CG.
Eur J Biochem. 2002 Jun;269(12):3076-85.
Structural and thermodynamic behavior of eukaryotic initiation factor 4E in supramolecular formation with 4E-binding protein 1 and mRNA cap analogue, studied by spectroscopic methods.
Shen X, Tomoo K, Uchiyama S, Kobayashi Y, Ishida T.
Chem Pharm Bull (Tokyo). 2001 Oct;49(10):1299-303.
Cell cycle-dependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1).
Heesom KJ, Gampel A, Mellor H, Denton RM.
Curr Biol. 2001 Sep 4;11(17):1374-9.
Regulation of human eIF4E by 4E-BP1: binding analysis using surface plasmon resonance.
Youtani T, Tomoo K, Ishida T, Miyoshi H, Miura K.
IUBMB Life. 2000 Jan;49(1):27-31.
Mutational analysis of sites in the translational regulator, PHAS-I, that are selectively phosphorylated by mTOR.
Yang D, Brunn GJ, Lawrence JC Jr.
FEBS Lett. 1999 Jun 25;453(3):387-90.
Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation.
Feigenblum D, Schneider RJ.
Mol Cell Biol. 1996 Oct;16(10):5450-7.
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function.
Pause A, Belsham GJ, Gingras AC, Donzé O, Lin TA, Lawrence JC Jr, Sonenberg N.
Nature. 1994 Oct 27;371(6500):762-7.
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on