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Surv Ophthalmol. 2007 Jan;52 Suppl 1:S41-8.

Preclinical efficacy of anecortave acetate.

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  • Discovery Research, Alcon Research, Ltd. Ft. Worth, Texas 76134, USA.

Abstract

Anecortave acetate is a unique ocular angiostatic cortisene that has broad-based anti-angiogenic activity in 14 different preclinical models of neovascularization, across multiple species and inducers of neovascularization. Anecortave acetate is being tested clinically for inhibition of choroidal neovascularization associated with age-related macular degeneration.

PMID:
17240256
[PubMed - indexed for MEDLINE]
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