Infect Dis Clin North Am. 1991 Dec;5(4):753-79.

Bacterial endotoxin: molecular relationships between structure and activity.

Rietschel ET, Seydel U, Zähringer U, Schade UF, Brade L, Loppnow H, Feist W, Wang MH, Ulmer AJ, Flad HD, et al.

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Forschungsinstitut Borstel, Institut für Experimentelle Biologie und Medizin, Germany.

Abstract

The significance of endotoxins in bacterial infection and their role as bacterial surface antigens (O antigens) have stimulated investigations into their chemical nature and the mechanisms of their biologic action during the last few decades. This article summarizes some of the recent results and emphasizes structure-activity relationships.

PMID:: 1723739; [PubMed - indexed for MEDLINE]

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Review Chemical structure, molecular conformation, and bioactivity of endotoxins. [Chem Immunol. 2000]
Review Chemical structure, molecular conformation, and bioactivity of endotoxins.
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[Lipopolysaccharides, endotoxins and O-antigens of gram-negative bacteria: chemical structure, biologic effect and serologic properties]. [Infection. 1987]
[Lipopolysaccharides, endotoxins and O-antigens of gram-negative bacteria: chemical structure, biologic effect and serologic properties].
Rietschel ET, Brade H. Infection. 1987 Mar-Apr; 15(2):133-41.
Review The chemical structure of bacterial endotoxin in relation to bioactivity. [Immunobiology. 1993]
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Rietschel ET, Kirikae T, Schade FU, Ulmer AJ, Holst O, Brade H, Schmidt G, Mamat U, Grimmecke HD, Kusumoto S. Immunobiology. 1993 Apr; 187(3-5):169-90.
[Lipopolysaccharides, endotoxins and O-antigens of gram-negative bacteria: chemical structure, biologic effect and serologic properties]. [Infection. 1987]
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Rietschel ET, Brade H. Infection. 1987; 15 Suppl 2:S76-84.
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