Graphs depict regions that exhibited a significant positive relation, r(14) > 0.50, P < 0.05, between the frequency of mind-wandering and the change in BOLD signal observed when people performed practiced relative to novel blocks. Participants’ BOLD difference scores (practiced – novel) are plotted against their standardized IPI daydreaming score. BOLD signal values for the two blocks were computed for each participant by averaging the signal in regions within 10 mm of the peak, from 4 TRs (10 s) until 10 TRs (22.5 s) after the block onset. (A) B. mPFC (BA 10; –6, 51, –9; k = 25); (B) B. precuneus and p. cingulate (BA 31, 7; –3, –45, 37; k = 72); (C) R. cingulate (BA 31; 7, –21, 51; k = 73); (D) L. insula (BA 13; –36, –16, 17; k = 10); (E) R. insula (BA 13; 47, 0, 4; k = 13). Activity is plotted on the average high-resolution anatomical image and displayed in neurological convention (left hemisphere is depicted on the left).