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Actas Urol Esp. 1991 Jul-Aug;15(4):357-60.

[Dimethyl sulfoxide in the treatment of interstitial cystitis].

[Article in Spanish]

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  • 1Servicio de Urología, Residencia General del Hospital La Fe, Valencia.


The paper presents the results obtained with endovesical dimethylsulphoxide in the treatment of interstitial cystitis in 30 women. Up to 80% patients showed clinical improvement with an average of 10 installations. Volume of maximal vesical capacity was increased in 24 patients (80%), the increase being greater than 100 cc in 10 cases. Presently, 24 (80%) patients remain under treatment, 14 with one instillation monthly and 10 once every six months. Six patients are fully asymptomatic without treatment after an average symptoms-free interval of 32 months. Since this is directly related to a decrease both in pain and miction frequency, the increase in vesical capacity appears to be a good improvement index. Dimethylsulphoxide in neither a healing nor a definite therapy but it seems to be effective in the management of this unknown disease.

[PubMed - indexed for MEDLINE]
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