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World J Surg Oncol. 2007 Jan 18;5:7.

"Pseudosarcoma" in a pregnant woman.

Author information

  • 1Royal Free and University College London Hospitals, Royal National Orthopaedic Hospital, Bone Tumour Unit, Brockley Hill, Stanmore, Middlesex, HA7 4L, UK. amarjitanand@doctors.org.uk

Abstract

BACKGROUND:

Intravascular fasciitis (IVF) is a rare benign condition characterised by reactive myofibroblastic proliferation arising from the superficial or deep fascia and involving arteries and/or veins. It is a distinct variant of the more common condition of nodular fasciitis, which possesses similar clinical and histological features to IVF, but lacks vascular invasion. A thorough review of the literature revealed 26 reported cases of IVF.

CASE PRESENTATION:

We report a case of IVF in a 16-week pregnant lady affecting the hypothenar eminence of the hand associated with the ulnar artery.

CONCLUSION:

The characteristic involvement of muscular arteries and veins by reactive myofibroblastic proliferation in IVF suggests a malignant component and often leads to an inappropriate diagnosis for this benign condition. We propose that hormone-related changes associated with pregnancy may play an important role in the aetiopathogenesis of this myofibroblastic lesion.

PMID:
17229326
[PubMed - indexed for MEDLINE]
PMCID:
PMC1794242
Free PMC Article
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