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Fetal Diagn Ther. 2007;22(3):206-8. Epub 2007 Jan 17.

Prenatal diagnosis of Bartter syndrome with biochemical examination of amniotic fluid: case report.

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  • 1Department of Perinatology, Clinics of Gynecology and Obstetrics, Haseki Education and Research Hospital, Istanbul, Turkey.


Antenatal Bartter syndrome typically presents with marked fetal polyuria that leads to polyhydramnios and premature delivery. In our case, polyhydramnios was detected at 26 weeks of gestation and amniotic fluid chloride level was high. Serial amnion-drains were performed. During indomethacine treatment, fetal bradycardia developed. The mother was given daily oral potassium to maintain normal serum level and prevent fetal arrhythmias. After birth, hypokalaemic alkalosis, low chloride, hyper-reninemia and hyperaldosteronemia were detected.

(c) 2007 S. Karger AG, Basel.

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