Anticipating the 1,000 dollar genome.

Genome Sequencing Center, Washington University School of Medicine, 4444 Forest Park Boulevard, St, Louis, MO 63108, USA. emardis@wustl.edu

A new generation of DNA-sequencing platforms will become commercially available over the next few years. These instruments will enable re-sequencing of human genomes at a previously unimagined throughput and low cost. Here, I examine why the 1,000 dollar human genome is an important goal for research and clinical diagnostics, and what will be required to achieve it.

PMID: 17224040 [PubMed - indexed for MEDLINE]

PMCID: PMC1779559