Abstract
A primary hepatic tumour occurred in a 21-year-old woman who had been taking oral contraceptives for two years; she was treated by partial hepatectomy. Part of the neoplasm showed features suggestive of focal nodular hyperplasia, while the remainder had the histological characteristics of a well-differentiated hepatocellular carcinoma. This is the first report of malignant transformation of a tumour in a patient taking oral contraceptives.
MeSH terms
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Adult
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Carcinoma, Hepatocellular / chemically induced*
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Carcinoma, Hepatocellular / pathology
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Carcinoma, Hepatocellular / surgery
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Contraceptives, Oral / adverse effects*
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Ethinyl Estradiol / adverse effects
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Female
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Hepatectomy
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Humans
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Liver Neoplasms / chemically induced*
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Liver Neoplasms / pathology
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Liver Neoplasms / surgery
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Megestrol / adverse effects
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Neoplasms, Multiple Primary / chemically induced*
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Neoplasms, Multiple Primary / pathology
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Neoplasms, Multiple Primary / surgery
Substances
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Contraceptives, Oral
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Ethinyl Estradiol
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Megestrol