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1: Handb Exp Pharmacol. 2007;(179):329-44.Click here to read Links

TRPM8.

Voets T, Owsianik G, Nilius B.

Laboratory of Physiology, KU Leuven, Campus Gasthuisberg O and N, 3000 Leuven, Belgium. Thomas.voets@med.kuleuven.be

Originally cloned as a prostate-specific protein, TRPM8 is now best known as a cold- and menthol-activated channel implicated in thermosensation. In this chapter we provide a brief review of current knowledge concerning the biophysical properties, gating mechanisms, pharmacology and (patho)physiology of this TRP channel.

PMID: 17217067 [PubMed - indexed for MEDLINE]

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