Cat's claw: an Amazonian vine decreases inflammati...[Complement Ther Clin Pract. 2007]

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1: Complement Ther Clin Pract. 2007 Feb;13(1):25-8. Epub 2006 Dec 13. Links

Cat's claw: an Amazonian vine decreases inflammation in osteoarthritis.

Hardin SR.

University of North Carolina at Charlotte, School of Nursing, 9201 University Blvd, Charlotte, NC 28223, USA. srhardin@email.uncc.edu

Cat's claw (Uncaria tomentosa and Uncaria guianesis) is a medicinal plant from the Amazon commonly used to treat disorders such as arthritis, gastritis and osteoarthritis. The mechanism of cat's claw appears to be as an inhibitor of TNFalpha and antioxidant. Understanding the processes in osteoarthritis may facilitate and clarify the potential role of cat's claw as a complementary therapy to assist in the reduction of pro-inflammatory mediators and effectors. The clinical relevance of this therapy as a viable modality of intervention will be discussed.

PMID: 17210508 [PubMed - indexed for MEDLINE]

Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis.
Inflamm Res. 2001 Sep; 50(9):442-8.

[Inflamm Res. 2001]
Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content.
Phytomedicine. 2002 May; 9(4):325-37.

[Phytomedicine. 2002]
ReviewToxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis.
Toxicol Rev. 2005; 24(1):11-35.

[Toxicol Rev. 2005]
Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection.
Free Radic Biol Med. 2000 Jul 1; 29(1):71-8.

[Free Radic Biol Med. 2000]
ReviewReview of antiviral and immunomodulating properties of plants of the Peruvian rainforest with a particular emphasis on Una de Gato and Sangre de Grado.
Altern Med Rev. 2001 Dec; 6(6):567-79.

[Altern Med Rev. 2001]
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