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Annu Rev Plant Biol. 2007;58:249-66.

The plant heterotrimeric G-protein complex.

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  • 1R. L. Juliano Structural Bioinformatics Core Facility, Departments of Biology and Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Abstract

Heterotrimeric G-protein complexes couple extracellular signals via cell surface receptors to downstream enzymes called effectors. Heterotrimeric G-protein complexes, together with their cognate receptors and effectors, operate at the apex of signal transduction. In plants, the number of G-protein complex components is dramatically less than in other multicellular eukaryotes. An understanding of how multiple signals propagate transduction through the G-protein node can be found in the unique structural and kinetic properties of the plant heterotrimeric G-protein complex. This review addresses these unique features and speculates on why the repertoire of G-protein signaling elements is dramatically simpler than that in all other multicellular eukaryotes.

PMID:
17201690
[PubMed - indexed for MEDLINE]
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