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Isolation and sequence determination of cDNA encoding the major structural protein of human peripheral myelin.
Department of Pediatrics, Akita University School of Medicine, Japan.
A full length cDNA of the major structural protein of peripheral myelin (P0 protein) has been isolated from a cDNA library of human fetus spinal cord. The clone is 1948 base pairs (bp) in length and contains a 744 bp open reading frame encoding a polypeptide of 248 residues including 29 signal peptide. The deduced amino acid sequence is highly homologous to P0 protein from other species.
PMID: 1719967 [PubMed - indexed for MEDLINE]
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Cited by 5 PubMed Central articles
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Molecular Characterization of Myelin Protein Zero in Xenopus laevis Peripheral Nerve: Equilibrium between Non-covalently Associated Dimer and Monomer.
Xie B, Luo X, Zhao C, Priest CM, Chan SY, O' Connor PB, Kirschner DA, Costello CE.
Int J Mass Spectrom. 2007 Dec 1; 268(2-3):304-315.
[Int J Mass Spectrom. 2007]
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Peripheral myelin of Xenopus laevis: role of electrostatic and hydrophobic interactions in membrane compaction.
Luo X, Cerullo J, Dawli T, Priest C, Haddadin Z, Kim A, Inouye H, Suffoletto BP, Avila RL, Lees JP, et al.
J Struct Biol. 2008 Apr; 162(1):170-83. Epub 2007 Nov 1.
[J Struct Biol. 2008]
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Cytoplasmic domain of zebrafish myelin protein zero: adhesive role depends on beta-conformation.
Luo X, Inouye H, Gross AA, Hidalgo MM, Sharma D, Lee D, Avila RL, Salmona M, Kirschner DA.
Biophys J. 2007 Nov 15; 93(10):3515-28. Epub 2007 Aug 10.
[Biophys J. 2007]
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