AIDS. 2007 Jan 11;21(2):239-41.

Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance.

Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM.

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AIDS Office, San Francisco Department of Public Health, San Francisco, California, USA.

Abstract

We determined whether methamphetamine use is associated with the increased prevalence of primary HIV drug resistance among a cohort of men who have sex with men recently infected with HIV. In multivariate analysis, we found that frequent methamphetamine use was strongly associated with primary non-nucleoside reverse transcriptase inhibitor resistance, but not with protease inhibitor or nucleoside reverse transcriptase inhibitor resistance. We postulate that this association may be caused by methamphetamine-associated treatment interruptions among source partners.

PMID:: 17197817; [PubMed - indexed for MEDLINE]

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Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance.

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