A Distinct type of heterochromatin within Drosophi...[Genetics. 2007]

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1: Genetics. 2007 Mar;175(3):1539-42. Epub 2006 Dec 28. Links

A Distinct type of heterochromatin within Drosophila melanogaster chromosome 4.

Haynes KA, Gracheva E, Elgin SC.

Department of Biology, Washington University, St. Louis, Missouri 63130, USA.

Studies of transcriptional gene silencing in Drosophila melanogaster suggest that most of chromosome 4 resembles pericentric heterochromatin. However, some modifiers of position-effect variegation, including chromosome 4 dosage and loss of SU(VAR)3-9, have different effects on silencing in pericentric vs. distal arm chromosome 4 heterochromatin, distinguishing these two heterochromatin types.

PMID: 17194780 [PubMed - indexed for MEDLINE]

PMCID: PMC1840055

The genomic silencing of position-effect variegation in Drosophila melanogaster: interaction between the heterochromatin-associated proteins Su(var)3-7 and HP1. [J Cell Sci. 2000]
Suppressors of position-effect variegation in Drosophila melanogaster affect expression of the heterochromatic gene light in the absence of a chromosome rearrangement. [Genome. 1998]
SU(VAR)3-9 is a conserved key function in heterochromatic gene silencing. [Genetica. 2003]
[Somatic pairing of homologs of the fourth chromosome as a reason for suppression of the Dubinin effect in Drosophila melanogaster] [Genetika. 1998]
Intercalary heterochromatin in Drosophila melanogaster polytene chromosomes and the problem of genetic silencing. [Genetica. 2003]
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A Distinct type of heterochromatin within Drosophila melanogaster chromosome 4.

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