Efficient designs for powering microscale devices with nanoscale biomolecular motors.

Department of Electrical Engineering and Computer Science, University of Michigan, 48109, USA.

Current MEMS and microfluidic designs require external power sources and actuators, which principally limit such technology. To overcome these limitations, we have developed a number of microfluidic systems into which we can seamlessly integrate a biomolecular motor, kinesin, that transports microtubules by extracting chemical energy from its aqueous working environment. Here we establish that our microfabricated structures, the self-assembly of the bio-derived transducer, and guided, unidirectional transport of microtubules are ideally suited to create engineered arrays for efficiently powering nano- and microscale devices.

PMID: 17193036 [PubMed - indexed for MEDLINE]