Department of Genetics, Cell Biology & Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA. neufeld@ahc.umn.edu
Components involved in vesicle trafficking processes such as secretion, endocytosis, and autophagy are gaining recognition as important regulators and effectors of target of rapamycin (TOR) signaling. A recent report by now implicates Pmr1, a secretory pathway Ca(2+)/Mn(2+) ATPase located in the Golgi apparatus, as a novel regulator of TOR and its downstream targets in yeast.