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Aging Male. 2006 Dec;9(4):207-13.

Age related variation of salivary testosterone values in healthy Japanese males.

Author information

  • 1School of International Liberal Studies, Waseda University, Japan. a.uchida@waseda.jp

Abstract

OBJECTIVE:

We examined age associated variation in salivary testosterone values among Japanese males as well as anthropometric measurements.

METHODS:

Salivary samples were collected in pretreated sodium azide treated tubes. The first series: 15-79-year-old males (n = 99); two morning and two evening samples were collected at home for two days. The second series: 90-year-old males (n = 29); one morning sample was collected. Testosterone values were determined using an iodine125-based radioimmunoassay kit modified for saliva.

RESULTS:

Results show 1) a significant decrease in salivary testosterone values from 20s to 40s and older, 2) no significant decline after 40 through 90 years old, 3) no significant age-related differences in the degree of intraindividual diurnal fluctuation across age groups of 40-70s, and 4) higher BMI is associated with the lower salivary testosterone among 40-70s.

CONCLUSIONS:

These results suggest that neither a constant decrease of salivary testosterone values or markedly reduced intraindividual fluctations are universal aspects of aging. Older males may maintain relatively high testosterone levels compared to younger men and a relatively 'robust' neuroendocrinological system.

PMID:
17178556
[PubMed - indexed for MEDLINE]
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