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Nat Chem Biol. 2007 Jan;3(1):8-11.

RNA learns from antisense.

Author information

  • 1Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, Texas 75390-9041, USA. david.corey@utsouthwestern.edu

Abstract

RNA interference provides powerful tools for controlling gene expression in cultured cells. Whether RNAi will provide similarly powerful drugs is unknown. Lessons from development of antisense oligonucleotide drugs may provide some clues.

PMID:
17173018
[PubMed - indexed for MEDLINE]
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