Eye (Lond). 2008 Feb;22(2):308-10. Epub 2006 Dec 15.

Familial central retinal vein occlusion.

Girmens JF, Scheer S, Héron E, Sahel JA, Tournier-Lasserve E, Paques M.

Source

Department of Ophthalmology of the Fondation Ophtalmologique Rothschild and of the Centre Hospitalier National des Quinze-Vingts, Université Pierre et Marie Curie, Paris, France.

Abstract

AIM:

To report four cases of central retinal vein occlusion (CRVO) in a French family.

PATIENTS AND METHODS:

Ophthalmological examination and medical work-up of seven members of the family.

RESULTS:

There were four cases of CRVO in two consecutive generations. Three of them had CRVO in both eyes. Arterial hypertension was present in two, associated to glaucoma in one. Medical work-up did not reveal additional risk factors.

CONCLUSIONS:

We report a case of familial clustering of CRVO. Our cases combined to other cases reported in the literature provide arguments for the existence in some subjects of a genetic predisposition of CRVO. Additional case series are however needed to confirm this hypothesis.

PMID:: 17173011; [PubMed - indexed for MEDLINE]

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