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Neurology. 2006 Dec 12;67(11):2063-5.

High seroprevalence of Epstein-Barr virus in children with multiple sclerosis.

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  • 1Brauweg 19, 37073 Goettingen, Germany. dani.pohl@gmx.net


We studied seroprevalence and concentrations of Epstein-Barr virus (EBV) antibodies in 147 pediatric patients with multiple sclerosis (MS) and paired controls. The children with MS showed a near-complete seropositivity for EBV antibody against virus capsid antigen (98.6% vs 72.1% in controls, p = 0.001) but did not display serologic evidence for a recent EBV infection. EBV antibody concentrations of pediatric patients with MS were significantly higher vs controls.

[PubMed - indexed for MEDLINE]
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