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Hawaii Med J. 2006 Sep;65(9):260-3.

Evaluation of cryptococcus laurentii meningitis in a patient with HIV infection: a case report and review of the literature.

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  • 1Department of Medicine, John A. Burns School of Medicine, University of Hawaii, 1356 Lusitana Street, 7th Fl, Honolulu, HI 96813, USA.


Cryptococcus neoformans is the most common cryptococci causing infection in humans. Non-neoformans cryptococci have generally been regarded as saprophytes and rarely reported as human pathogens. We report a probable case of Cryptococcus laurentii meningitis in a HIV-infected patient and reviewed the literature on risk factors and treatment of this infection in humans. This patient was successfully treated with amphotericin B followed by fluconazole. Awareness of the emerging antifungal-resistant C. laurentii strains, as reported in the literature, should be emphasized, especially in immunocompromised patients.

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