Source
Department of Operative Dentistry and Periodontology, Albert-Ludwigs-University of Freiburg, Germany. markus.altenburger@uniklinik-freiburg.de
Abstract
PURPOSE:
The purpose of this cross-over, double-blind, placebo-controlled, randomised in situ study was to evaluate the remineralisation of demineralised enamel specimens using a CHX/NaF mouthrinse in comparison with a CHX- and a placebo-mouthrinse.
MATERIALS AND METHODS:
Twenty-four volunteers received intraoral appliances with mounted demineralised enamel specimens. They rinsed their mouths twice a day (10 ml for 1 minute) with the respective preparation. After 14 days, the in situ mineral gain and fluoride uptake were determined.
RESULTS:
Mineral gain was significantly higher after using CHX/F mouthrinse (358.4 +/- 372.1 Vol.% X microm) compared with CHX (95.6+/-192.2 Vol.% X microm) and placebo treatment (80.8 +/- 159.6 Vol.% x microm). Moreover, CHX/F treatment (2751.1+/-1494.9 microg/cm(3)) resulted in a significantly higher fluoride uptake compared with CHX- (83.8+/-94.0 microg/cm(3)) and placebo- (136.6+/-137.3 microg/cm(3)) mouthrinses.
CONCLUSION:
The in situ study approves that using a CHX/F mouthrinse supports the remineralisation of initial carious lesions.