Fam Community Health. 2007 Jan-Mar;30(1):50-62.

Selected genetic disorders affecting Ashkenazi Jewish families.

Source

School of Dentistry, Division of Public Health, Marquette University, Milwaukee, WI, USA. lenorewein@aol.com

Abstract

Ashkenazi Jews of Central and Eastern European ancestry have a disproportionately high prevalence of several autosomal recessive genetic disorders. This article describes these 9 disorders and their genetic inheritance patterns: Bloom syndrome; Canavan disease; cystic fibrosis; familial dysautonomia; Fanconi anemia; Gaucher disease; Mucolipidosis IV; Niemann-Pick disease; and Tay-Sachs disease. Genetic testing, counseling, and family planning options for the at-risk population are described. The role of the community health nurse is addressed.

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Selected genetic disorders affecting Ashkenazi Jewish families.

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